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2023 NFL Week 6 odds, predictions: Picks, lines, spreads for every game

The Detroit Lions (4-1) will visit the Tampa Bay Buccaneers (3-1) in a battle between two division leaders, highlighting the Week 6 schedule (4:25 p.m. ET Sunday on FOX and the FOX Sports App).

Another key Week 6 contest features the Indianapolis Colts and Jacksonville Jaguars, the AFC South Division co-leaders at 3-2.

Closing out the slate is the Dallas Cowboys (3-2) visiting the Los Angeles Chargers (2-2) on Monday Night Football.

Here’s everything you need to know about the NFL odds for Week 6 — the point spread, moneyline and total Over/Under.

All times ET

BYES: Packers, Steelers 

THURSDAY’S GAME

Broncos at Chiefs (8:15 p.m., Amazon Prime Video)

Point spread: Chiefs -10.5 (Chiefs favored to win by more than 10.5 points, otherwise Broncos cover)Moneyline: Chiefs -573 favorites to win (bet $10 to win $11.75 total); Broncos +419 underdogs to win (bet $10 to win $51.90 total)Total scoring Over/Under: 47 points scored by both teams combined

49ers & Chiefs swap spots in Nick’s Tiers

Day Week Blank Calendar With Time Slots Printable  Excel
Day Week Blank Calendar With Time Slots Printable Excel

Nick Wright, Chris Broussard, Kevin Wildes and Greg Jennings release the latest edition of Nick’s NFL Tiers ranking all 32 teams.

SUNDAY’S GAMES

Ravens vs. Titans in London (9:30 a.m., NFL)

Point spread: Ravens -4 (Ravens favored to win by more than 4 points, otherwise Titans cover)Moneyline: Ravens -202 favorites to win (bet $10 to win $14.95 total); Titans +168 underdogs to win (bet $10 to win $26.80 total)Total scoring Over/Under: 41 points scored by both teams combined

Vikings at Bears (1 p.m., FOX and FOX Sports App)

Point spread: Vikings -2.5 (Vikings favored to win by more than 2.5 points, otherwise Bears cover)Moneyline: Vikings -146 favorites to win (bet $10 to win $16.85 total); Bears +124 underdogs to win (bet $10 to win $22.40 total)Total scoring Over/Under: 44.5 points scored by both teams combined

49ers at Browns (1 p.m., FOX and FOX Sports App)

Point spread: 49ers -7 (49ers favored to win by more than 7 points, otherwise Browns cover)Moneyline: 49ers -314 favorites to win (bet $10 to win $13.18 total); Browns +248 underdogs to win (bet $10 to win $34.80 total)Total scoring Over/Under: 37 points scored by both teams combined

Saints at Texans (1 p.m., FOX and FOX Sports App)

Point spread: Saints -1.5 (Saints favored to win by more than 1.5 points, otherwise Texans cover)Moneyline: Saints -124 favorites to win (bet $10 to win $18.06 total); Texans +103 underdogs to win (bet $10 to win $20.30 total)Total scoring Over/Under: 42.5 points scored by both teams combined

Commanders at Falcons (1 p.m., CBS)

Point spread: Falcons -2.5 (Falcons favored to win by more than 2.5 points, otherwise Commanders cover)Moneyline: Falcons -142 favorites to win (bet $10 to win $17.04 total); Commanders +120 underdogs to win (bet $10 to win $22 total)Total scoring Over/Under: 42.5 points scored by both teams combined

Seahawks at Bengals (1 p.m., CBS)

Point spread: Bengals -2.5 (Bengals favored to win by more than 2.5 points, otherwise Seahawks cover)Moneyline: Bengals -152 favorites to win (bet $10 to win $16.58 total); Seahawks +129 underdogs to win (bet $10 to win $22.90 total)Total scoring Over/Under: 45 points scored by both teams combined

Panthers at Dolphins (1 p.m., CBS)

Point spread: Dolphins -13.5 (Dolphins favored to win by more than 13.5 points, otherwise Panthers cover)Moneyline: Dolphins -852 favorites to win (bet $10 to win $11.17 total); Panthers +571 underdogs to win (bet $10 to win $67.10 total)Total scoring Over/Under: 48.5 points scored by both teams combined

Colts at Jaguars (1 p.m., CBS)

Point spread: Jaguars -4 (Jaguars favored to win by more than 4 points, otherwise Colts cover)Moneyline: Jaguars -204 favorites to win (bet $10 to win $14.90 total); Colts +169 underdogs to win (bet $10 to win $26.90 total)Total scoring Over/Under: 45.5 points scored by both teams combined

Patriots at Raiders (4:05 p.m., CBS)

Point spread: Raiders -3 (Raiders favored to win by more than 3 points, otherwise Patriots cover)Moneyline: Raiders -163 favorites to win (bet $10 to win $16.13 total); Patriots +138 underdogs to win (bet $10 to win $23.80 total)Total scoring Over/Under: 41.5 points scored by both teams combined

Cardinals at Rams (4:25 p.m., FOX and FOX Sports App)

Point spread: Rams -7 (Rams favored to win by more than 7 points, otherwise Cardinals cover)Moneyline: Rams -316 favorites to win (bet $10 to win $13.16 total); Cardinals +251 underdogs to win (bet $10 to win $35.10 total)Total scoring Over/Under: 48.5 points scored by both teams combined

Eagles at Jets (4:25 p.m., FOX and FOX Sports App)

Point spread: Eagles -7 (Eagles favored to win by more than 7 points, otherwise Jets cover)Moneyline: Eagles -308 favorites to win (bet $10 to win $13.25 total); Jets +243 underdogs to win (bet $10 to win $34.30 total)Total scoring Over/Under: 41 points scored by both teams combined

Lions at Buccaneers (4:25 p.m., FOX and FOX Sports App)

Point spread: Lions -3 (Lions favored to win by more than 3 points, otherwise Buccaneers cover)Moneyline: Lions -170 favorites to win (bet $10 to win $15.88 total); Buccaneers +142 underdogs to win (bet $10 to win $24.20 total)Total scoring Over/Under: 43.5 points scored by both teams combined

Giants at Bills (8:20 p.m., NBC)

Point spread: Bills -14 (Bills favored to win by more than 14 points, otherwise Giants cover)Moneyline: Bills -895 favorites to win (bet $10 to win $11.12 total); Giants +592 underdogs to win (bet $10 to win $69.20 total)Total scoring Over/Under: 44.5 points scored by both teams combined

MONDAY’S GAME

Cowboys at Chargers (8:15 p.m. ET, ESPN/ABC)

Point spread: Cowboys -2.5 (Cowboys favored to win by more than 2.5 points, otherwise Chargers cover)Moneyline: Cowboys -133 favorites to win (bet $10 to win $17.52 total); Chargers +113 underdogs to win (bet $10 to win $21.30 total)Total scoring Over/Under: 51 points scored by both teams combined

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Weekly Schedule Template with AM and PM - Week of September ,
Weekly Schedule Template with AM and PM – Week of September ,
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Free Blank Calendar Templates – Smartsheet